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Search results 1 to 100 out of 324 for Zw10

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
9183 | ZW10
Type: gene
Organism: human
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Gene
779461 | zw10
Type: gene
Organism: frog, western clawed
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Gene
363059 | Zw10
Type: gene
Organism: rat
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Gene
479433 | ZW10
Type: gene
Organism: dog, domestic
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Gene
451554 | ZW10
Type: gene
Organism: chimpanzee
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Gene
511084 | ZW10
Type: gene
Organism: cattle
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Gene
395275 | ZW10
Type: gene
Organism: chicken
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Gene
393110 | zw10
Type: gene
Organism: zebrafish
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Gene
694436 | ZW10
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1349478 | Zw10
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9298984 | J:51740
First Author: Starr DA
Year: 1997
Journal: J Cell Biol
Title: Conservation of the centromere/kinetochore protein ZW10.
Volume: 138
Issue: 6
Pages: 1289-301
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Publication
31250100 | J:301696
First Author: Park Y
Year: 2019
Journal: Histochem Cell Biol
Title: Zw10 is a spindle assembly checkpoint protein that regulates meiotic maturation in mouse oocytes.
Volume: 152
Issue: 3
Pages: 207-215
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Gene
11130 | ZWINT
Type: gene
Organism: human
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Protein
Q9CQU5
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: false
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Protein
A0A1W2P7M1
Organism: Mus musculus/domesticus
Length: 126  
Fragment?: true
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Protein Coding Gene
MGP_CAROLIEiJ_G0032174 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034768 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034749 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034451 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1349478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035261 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034582 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034523 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034663 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033886 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015042 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033313 | -
Type: protein_coding_gene
Organism: Mus spretus
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Protein
A0A1L1SST9
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Publication
16732327 | -
First Author: Lin YT
Year: 2006
Journal: Oncogene
Title: Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.
Volume: 25
Issue: 52
Pages: 6901-14
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Protein
O54692
Organism: Mus musculus/domesticus
Length: 779  
Fragment?: false
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Gene
101904477 | LOC101904477
Type: gene
Organism: cattle
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Publication
11146659 | -
First Author: Basto R
Year: 2000
Journal: Nat Cell Biol
Title: Rough deal and Zw10 are required for the metaphase checkpoint in Drosophila.
Volume: 2
Issue: 12
Pages: 939-43
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
15824131 | -
First Author: Kops GJ
Year: 2005
Journal: J Cell Biol
Title: ZW10 links mitotic checkpoint signaling to the structural kinetochore.
Volume: 169
Issue: 1
Pages: 49-60
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UniProt Feature
UniProt Feature
Begin: 1
Description: ZW10 interactor
Type: chain
End: 252
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Publication
15485811 | -
First Author: Wang H
Year: 2004
Journal: J Biol Chem
Title: Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling.
Volume: 279
Issue: 52
Pages: 54590-8
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Publication
21775627 | -
First Author: Kasuboski JM
Year: 2011
Journal: Mol Biol Cell
Title: Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores.
Volume: 22
Issue: 18
Pages: 3318-30
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Protein Domain
IPR029092 | Zwint-1
Type: Family
Description: ZW10 interactor (also known as Zwint-1) is part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity []. It recruits ZW10 to unattached kinetochores at prometaphase []. It is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores []. It can be phosphoryltated by Aurora B (AurB) kinase [].
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Publication
16505164 | -
First Author: Varma D
Year: 2006
Journal: J Cell Biol
Title: Role of the kinetochore/cell cycle checkpoint protein ZW10 in interphase cytoplasmic dynein function.
Volume: 172
Issue: 5
Pages: 655-62
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Publication
17102640 | -
First Author: Vallee RB
Year: 2006
Journal: Cell Cycle
Title: ZW10 function in mitotic checkpoint control, dynein targeting and membrane trafficking: is dynein the unifying theme?
Volume: 5
Issue: 21
Pages: 2447-51
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Gene
477579 | ZWINT
Type: gene
Organism: dog, domestic
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Gene
450469 | ZWINT
Type: gene
Organism: chimpanzee
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Gene
257644 | Zwint
Type: gene
Organism: rat
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Gene
514564 | ZWINT
Type: gene
Organism: cattle
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Gene
702198 | ZWINT
Type: gene
Organism: macaque, rhesus
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Gene
103694101 | LOC103694101
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1289227 | Zwint
Type: protein_coding_gene
Organism: mouse, laboratory
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UniProt Feature
UniProt Feature
Begin: 2
Description: Centromere/kinetochore protein zw10 homolog
Type: chain
End: 779
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Publication
18268100 | -
First Author: Famulski JK
Year: 2008
Journal: J Cell Biol
Title: Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint.
Volume: 180
Issue: 3
Pages: 507-20
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Publication
17509882 | -
First Author: Yang Z
Year: 2007
Journal: Curr Biol
Title: Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint.
Volume: 17
Issue: 11
Pages: 973-80
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Protein Domain
IPR009361 | RZZ-complex_Zw10
Type: Family
Description: Zeste white 10 (ZW10) was initially identified as a mitoticcheckpoint protein involved in chromosome segregation, and then implicated in targeting cytoplasmic dynein and dynactin to mitotic kinetochores, but it is also important in non-dividing cells. These include cytoplasmic dynein targeting to Golgi and other membranes, and SNARE-mediated ER-Golgi trafficking [, , ]. Dominant-negative ZW10, anti-ZW10 antibody, and ZW10 RNA interference (RNAi) cause Golgi dispersal. ZW10 RNAi also disperse endosomes and lysosomes [].Drosophila kinetochore components Rough deal (Rod) and Zw10 are required for the proper functioning of the metaphase checkpoint in flies and mammals [, ]. The eukaryotic spindle assembly checkpoint (SAC) monitors microtubule attachment to kinetochores and prevents anaphase onset until all kinetochores are aligned on the metaphase plate. It is an essential surveillance mechanism that ensures high fidelity chromosome segregation during mitosis. In higher eukaryotes, cytoplasmic dynein is involved in silencing the SAC by removing the checkpoint proteins Mad2 and the Rod-Zw10-Zwilch complex (RZZ) from aligned kinetochores [, , ].
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Gene
443575 | zw10.S
Type: gene
Organism: frog, African clawed
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Gene
445850 | zw10.L
Type: gene
Organism: frog, African clawed
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Gene
120097432 | Zwint-ps1
Type: gene
Organism: rat
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Publication
22685323 | -
First Author: Wainman A
Year: 2012
Journal: J Cell Sci
Title: The Drosophila RZZ complex - roles in membrane trafficking and cytokinesis.
Volume: 125
Issue: Pt 17
Pages: 4014-25
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Allele
Zw10<+> | MGI:2438375
   
Name: zw10 kinetochore protein; wild type
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Allele
Zwint<+> | MGI:3048779
   
Name: ZW10 interactor; wild type
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Protein Coding Gene
MGP_CAROLIEiJ_G0015431 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017284 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017107 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1289227 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017184 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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