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Allele : Actb<tm1(INSR)Dac> actin, beta; targeted mutation 1, Dominico Accili

Primary Identifier  MGI:4831148 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, No functional change Gene  Actb
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An IRES, floxed neomycin selection cassette with a polyadenylation signal, and a human insulin receptor cDNA were inserted downstream of the stop codon of the endogenous gene. Expression of the inserted INSR cDNA requires cre excision of the neomycin cassette.
  • mutations:
  • Insertion
  • synonyms:
  • beta/INSR,
  • beta/INSR
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories