| First Author | Svare B | Year | 1988 |
| Journal | Horm Behav | Volume | 22 |
| Issue | 1 | Pages | 90-9 |
| PubMed ID | 3350480 | Mgi Jnum | J:35291 |
| Mgi Id | MGI:82741 | Doi | 10.1016/0018-506x(88)90033-5 |
| Citation | Svare B (1988) Genotype modulates the aggression-promoting quality of progesterone in pregnant mice. Horm Behav 22(1):90-9 |
| abstractText | During late pregnancy, female mice of the DBA/2J inbred strain are more likely to exhibit aggressive behavior toward a standard stimulus intruder male than C57BL/6J females. This strain difference can not be accounted for by differences in circulating levels of progesterone (P) since pregnant DBA/2J and C57BL/6J females exhibit similar patterns of the steroid throughout pregnancy. Upon receiving subcutaneously implanted Silastic capsules containing P, virgin DBA/2J mice are more likely than virgin C57BL/6J to respond to the steroid by exhibiting aggression. Strain differences in the aggressive behavior exhibited by pregnant mice may be related to genotype-based variation in central neural tissue sensitivity to P. |
