| Primary Identifier | MGI:1918677 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 108837 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable protein kinase binding activity and protein tyrosine kinase inhibitor activity. Predicted to be involved in negative regulation of protein phosphorylation. Predicted to act upstream of or within release of sequestered calcium ion into cytosol. Predicted to be located in membrane. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Orthologous to human IBTK (inhibitor of Bruton tyrosine kinase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit more sustained calcium fluxes in spleen cells stimulated with IgM. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
