| Primary Identifier | MGI:95666 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 14468 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables GMP binding activity and GTPase activity. Involved in several processes, including cytolysis in another organism; positive regulation of pyroptosis; and response to bacterium. Acts upstream of or within adhesion of symbiont to host; cellular response to interferon-beta; and defense response to other organism. Located in cytoplasmic vesicle and symbiont-containing vacuole membrane. Orthologous to several human genes including GBP2 (guanylate binding protein 2). PHENOTYPE: Mice homozygous for a targeted allele exhibit increased susceptibility to bacterial infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
