Primary Identifier | MGI:2445686 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Xbp1 |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was disrupted by the insertion of a neomycin selection cassette such that translation would produce a protein containing 80 amino terminal residues as well as 5 residues derived from linker sequence. RT-PCR indicated that normal transcript was absent in homozygous mutant embryos. |