Primary Identifier | MGI:3575158 | Allele Type | Chemically induced (ENU) |
Gene | Scarb1 | Inheritance Mode | Dominant |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A T to A transversion is located in exon 4 at 536 bp from the start site. This transversion results in a isoleucine to asparagine amino acid change. Western blot analysis indicates that protein expression in the liver of homozygous mice is reduced compared to wild-type controls but levels in the adrenals and ovaries are similar to wild-type controls. |