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Allele : Scarb1<Hlb398> scavenger receptor class B, member 1; heart, lung and blood 398

Primary Identifier  MGI:3575158 Allele Type  Chemically induced (ENU)
Gene  Scarb1 Inheritance Mode  Dominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  A T to A transversion is located in exon 4 at 536 bp from the start site. This transversion results in a isoleucine to asparagine amino acid change. Western blot analysis indicates that protein expression in the liver of homozygous mice is reduced compared to wild-type controls but levels in the adrenals and ovaries are similar to wild-type controls.
  • mutations:
  • Single point mutation
  • synonyms:
  • Scarb1<I179N>,
  • Scarb1<I179N>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele