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Protein Coding Gene : Pdc phosducin

Primary Identifier  MGI:98090 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  20028
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to be involved in regulation of G protein-coupled receptor signaling pathway. Predicted to act upstream of or within visual perception. Located in photoreceptor outer segment. Is expressed in several structures, including central nervous system; foot; skeleton; and spinal nerve plexus. Orthologous to human PDC (phosducin).
PHENOTYPE: Homozygous null mice display normal retinal morphology and rod function with reduced transducin (Gnat1) translocation. Mice homozygous for a different knock-out allele exhibit large pupils, increased blood pressure, age-related vascular smooth muscle hypertrophy, and stress-induced hypertension. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-13205,
  • MGD-MRK-14115,
  • phosducin,
  • Rpr-1,
  • Rpr1,
  • MGD-MRK-14116,
  • Pdc,
  • rod photoreceptor 1

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Genome

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2 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

Gene --> Expression annotations

Phenotype

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Disease

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