| Primary Identifier | MGI:102952 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 13139 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables ATP-dependent diacylglycerol kinase activity and phospholipid binding activity. Predicted to be involved in glycerolipid metabolic process; intracellular signal transduction; and lipid phosphorylation. Predicted to act upstream of or within lipid metabolic process. Located in cytosol and plasma membrane. Is expressed in several structures, including alimentary system; cranial ganglion; integumental system; respiratory system; and sensory organ. Orthologous to human DGKA (diacylglycerol kinase alpha). PHENOTYPE: Homozygous mutation of this gene results in impaired induction of T cell anergy. T cells stimulated in anergy producing conditions show increased proliferation and interleukin 2 production. Mice homozygous for a transgenic gene disruption exhibit male infertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
