Primary Identifier | IPR042486 | Type | Homologous_superfamily |
Short Name | Arabino_trans_C_2 |
description | Arabinosyltransferaseis involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol [].This superfamily represents the subdomain 2 of the C-terminal of arabinosyltransferase. Structurally, this domain is composed of 3 alpha helices and 10 beta strands, arranged into a jelly-roll beta sandwich. |