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Protein Coding Gene : Ipo11 importin 11

Primary Identifier  MGI:2442377 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  76582
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables nuclear import signal receptor activity. Acts upstream of or within ribosomal protein import into nucleus. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nuclear envelope. Is expressed in several structures, including early conceptus; germ cell of gonad; and islets of Langerhans. Orthologous to human IPO11 (importin 11).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators]
  • synonyms:
  • AI314624,
  • MGI:2145456,
  • importin 11,
  • expressed sequence AW555235,
  • MGI:2145201,
  • E330021B14Rik,
  • RIKEN cDNA 1700081H05 gene,
  • expressed sequence AI314624,
  • RIKEN cDNA E330021B14 gene,
  • AW555235,
  • MGI:1923832,
  • Ipo11,
  • MGI:1920761,
  • 1700081H05Rik,
  • RIKEN cDNA 2510001A17 gene,
  • Ranbp11,
  • 2510001A17Rik

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