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Protein Coding Gene : Thrsp thyroid hormone responsive

Primary Identifier  MGI:109126 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  21835
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables molecular function inhibitor activity and protein homodimerization activity. Involved in regulation of triglyceride biosynthetic process. Acts upstream of or within response to bacterium. Located in cytosol. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and sensory organ. Orthologous to human THRSP (thyroid hormone responsive).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased triglyceride during lactation and in milk produced as well as decreased de novo lipid biosynthesis in mammary tissue. [provided by MGI curators]
  • synonyms:
  • Spot 14,
  • Thrsp,
  • MGD-MRK-38170,
  • thyroid hormone responsive,
  • S14

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For