Primary Identifier | IPR026544 | Type | Family |
Short Name | SMO |
description | This entry represents smoothened (SMO) and its homologues, which are related to the frizzled protein family. Smoothened is a G protein-coupled receptor that is involved in the hedgehog signalling pathway. Smoothened probably associates with the patched protein to transduce the hedgehog's proteins signal []. Mutated smoothened can function as an oncogene []. |