Primary Identifier | MGI:97877 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 19660 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables lipid binding activity. Predicted to be involved in fatty acid transport. Predicted to act upstream of or within retinoid metabolic process. Is active in cytosol. Is expressed in embryo; intestine; lower jaw tooth; and tooth. Orthologous to human RBP2 (retinol binding protein 2). PHENOTYPE: Saturable vitamin A (retinol) uptake is impaired in homozygous mutant mice. Serum retinol levels are unaffected when with normal dietary intake, however, pups of homozygous dams fed a marginal retinol diet show increased neonatal lethality due to inadequate retinal transport to the fetus. [provided by MGI curators] |