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Protein Coding Gene : Rbp2 retinol binding protein 2, cellular

Primary Identifier  MGI:97877 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  19660
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables lipid binding activity. Predicted to be involved in fatty acid transport. Predicted to act upstream of or within retinoid metabolic process. Is active in cytosol. Is expressed in embryo; intestine; lower jaw tooth; and tooth. Orthologous to human RBP2 (retinol binding protein 2).
PHENOTYPE: Saturable vitamin A (retinol) uptake is impaired in homozygous mutant mice. Serum retinol levels are unaffected when with normal dietary intake, however, pups of homozygous dams fed a marginal retinol diet show increased neonatal lethality due to inadequate retinal transport to the fetus. [provided by MGI curators]
  • synonyms:
  • Rbp2,
  • retinol binding protein 2, cellular,
  • MGD-MRK-13793,
  • MGD-MRK-2132,
  • cellular retinol binding protein II,
  • MGD-MRK-13788,
  • Crbp-2,
  • Rbp-2,
  • CrbpII

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For