First Author | Horvath DH | Year | 1996 |
Journal | Gene | Volume | 171 |
Issue | 2 | Pages | 305-6 |
PubMed ID | 8666294 | Mgi Jnum | J:33634 |
Mgi Id | MGI:81112 | Doi | 10.1016/0378-1119(96)00033-9 |
Citation | Horvath DH, et al. (1996) Probable exclusion of the cortexin-encoding gene as a candidate for mouse neurological mutants: nervous, tottering and motor neuron degeneration. Gene 171(2):305-6 |
abstractText | We have tested the gene encoding cortexin, Ctxn, which maps to chromosome 8, as a candidate for the mouse neurological mutants: nervous (nr), tottering (tg) plus tottering-leaner (tg(la)), and motor neuron degeneration (mnd) by Northern blot analysis of brain poly(A)(+) RNA and direct polymerase chain reaction (PCR) sequencing. No difference from wild-type was seen in any of these mutants. Based upon these observations, we conclude that Ctxn is not involved in the genetic defects found in nr, tg or mnd mice. |