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Allele : Tdg<tm2.1Abc> thymine DNA glycosylase; targeted mutation 2.1, Alfonso Bellacosa
Primary Identifier  MGI:5285106 Allele Type  Targeted
Attribute String  Not Specified Gene  Tdg
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 3. Exon 4 was replaced with a modified exon 4 that contains nucleotide substitutions (AAC to GCC) that result in the amino acid substitution of alanine for asparagine at position 151 (N151A). An additional loxP site was inserted upstream of exon 7. Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Tdg<N151A>,
  • Tdg<N151A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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