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Publication : Expression of murine novel zinc finger proteins highly homologous to Drosophila ovo gene product in testis.

First Author  Masu Y Year  1998
Journal  FEBS Lett Volume  421
Issue  3 Pages  224-8
PubMed ID  9468311 Mgi Jnum  J:45546
Mgi Id  MGI:1195596 Doi  10.1016/s0014-5793(97)01567-6
Citation  Masu Y, et al. (1998) Expression of murine novel zinc finger proteins highly homologous to Drosophila ovo gene product in testis. FEBS Lett 421(3):224-8
abstractText  We have cloned two isoforms of cDNAs encoding novel zinc finger proteins. One form encodes a 274-amino acid protein containing an acidic amino acid and serine-rich domain and a zinc finger domain which shows high sequence homology to that of Drosophila Ovo protein. The other form encodes a 179-amino acid protein containing only the zinc finger domain. Expression of both proteins possessing an antigenic epitope in COS cells revealed that they are localized in the nucleus. The 1.3-kbp mRNAs are predominantly expressed in testis, and the expression increases from 3 weeks postnatal, implying that these proteins may play important roles in the development of the testes.
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