First Author | Masu Y | Year | 1998 |
Journal | FEBS Lett | Volume | 421 |
Issue | 3 | Pages | 224-8 |
PubMed ID | 9468311 | Mgi Jnum | J:45546 |
Mgi Id | MGI:1195596 | Doi | 10.1016/s0014-5793(97)01567-6 |
Citation | Masu Y, et al. (1998) Expression of murine novel zinc finger proteins highly homologous to Drosophila ovo gene product in testis. FEBS Lett 421(3):224-8 |
abstractText | We have cloned two isoforms of cDNAs encoding novel zinc finger proteins. One form encodes a 274-amino acid protein containing an acidic amino acid and serine-rich domain and a zinc finger domain which shows high sequence homology to that of Drosophila Ovo protein. The other form encodes a 179-amino acid protein containing only the zinc finger domain. Expression of both proteins possessing an antigenic epitope in COS cells revealed that they are localized in the nucleus. The 1.3-kbp mRNAs are predominantly expressed in testis, and the expression increases from 3 weeks postnatal, implying that these proteins may play important roles in the development of the testes. |