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Allele : Chd4<tm1Kge> chromodomain helicase DNA binding protein 4; targeted mutation 1, Katia Georgopoulos

Primary Identifier  MGI:3653109 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Chd4
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert loxP sites to flank exons 12 through 21 of the locus. Frt sites flanked a neo included in the vector in intron 11. The floxed locus encompasses the ATPase domain, required for the remodeling activity. Splicing of exon 11 to exon 22 would putatively generate an out of frame transcript, possibly resulting in a truncated protein.
  • mutations:
  • Insertion
  • synonyms:
  • Mi-2B<LoxPNeo+>,
  • Mi-2B<LoxPNeo+>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele