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Protein Coding Gene : Trmt61a tRNA methyltransferase 61A

Primary Identifier  MGI:2443487 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  328162
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable mRNA (adenine-N1-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to act upstream of or within methylation and tRNA processing. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus. Orthologous to human TRMT61A (tRNA methyltransferase 61A).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased CD4+ T cells and stimulated T cell proliferation. [provided by MGI curators]
  • synonyms:
  • AI606093,
  • tRNA methyltransferase 61A,
  • 6720458F09Rik,
  • RIKEN cDNA 6720458F09 gene,
  • MGI:2144866,
  • Trmt61a,
  • expressed sequence AI606093

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