Primary Identifier | MGI:1915703 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 68453 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables lipase binding activity; lipoprotein particle binding activity; and protein transporter activity. Involved in several processes, including cholesterol homeostasis; positive regulation of chylomicron remnant clearance; and protein transport. Acts upstream of or within lipid transport. Located in apical plasma membrane; basolateral plasma membrane; and external side of plasma membrane. Human ortholog(s) of this gene implicated in familial GPIHBP1 deficiency. Orthologous to human GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit milky plasma due to increased triglyceride and cholesterol levels. [provided by MGI curators] |