Primary Identifier | MGI:5902220 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Braf |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-Neo-STOP cassette flanked by loxP sites was inserted in intron 6 and a glutamine to arginine substitution at amino acid 241 (Q241R) was inserted into exon 7 via homologous recombination. The mutant transcript is expressed only after cre-mediated recombination. |