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Publication : Cloning and expression of the chick p63 gene.

First Author  Yasue A Year  2001
Journal  Mech Dev Volume  100
Issue  1 Pages  105-8
PubMed ID  11118893 Mgi Jnum  J:66537
Mgi Id  MGI:1928598 Doi  10.1016/s0925-4773(00)00504-9
Citation  Yasue A, et al. (2001) Cloning and expression of the chick p63 gene. Mech Dev 100(1):105-8
abstractText  We have isolated a chick cDNA for p63, a member of the p53 transcription factor family. This cDNA encodes a protein of 582 amino acids for an alpha isoform in the C-terminal region, while lacking the N-terminal transactivation domain. The chick p63 gene is first expressed in the prospective cutaneous ectoderm at stage 6 and later in the developing epithelia. The p63 expression is intense in specialized epithelial structures, such as apical ectodermal ridge of the limb bud, epithelia of branchial arches and feather buds. Furthermore, we have found that the transcripts are detected in the interdigital epithelium, intersomite epithelium, and epaxial dermamyotome.
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