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Allele : Lipe<tm2Rze> lipase, hormone sensitive; targeted mutation 2, Rudolf Zechner

Primary Identifier  MGI:3832721 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Lipe
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin selection cassette was inserted in intron 1 and an additional loxP site was inserted 3' to exon 7. The resulting targeted ES cells were subjected to transient cre expression. The neomycin selection cassette was deleted leaving exons 2 through 7 flanked by loxP sites. In addition to this allele, transient expression provided recombinant ES cells in which exons 2-7 were also deleted. These cells were used to produce Lipetm1Rze.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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7 Publication categories

Trail: Allele