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Protein Domain : 8-oxoguanine DNA glycosylase/AP lyase Ogg

Primary Identifier  IPR012092 Type  Family
Short Name  DNA_glyclase/AP_lyase_Ogg
description  This entry represents bifunctional, thermostable 8-oxoguanine DNA glycosylase/DNA lyase enzymes (OGG or OG glycosylases), which are involved in base excision repair of DNAdamaged by oxidation or by mutagenic agents []. Most damage to bases in DNA is repaired by the base excision repair pathway []. These enzymes have both DNA glycosylase activity () and AP lyase activity (). OGG1 enzymes are active only towards the removal of 8-oxoguanine [].

0 Child Features

0 Parent Features

0 Protein Domain Regions