First Author | Takeshita H | Year | 1997 |
Journal | Biochem Mol Biol Int | Volume | 42 |
Issue | 1 | Pages | 65-75 |
PubMed ID | 9192086 | Mgi Jnum | J:41312 |
Mgi Id | MGI:893737 | Doi | 10.1080/15216549700202441 |
Citation | Takeshita H, et al. (1997) Mouse deoxyribonuclease I (DNase I): biochemical and immunological characterization, cDNA structure and tissue distribution. Biochem Mol Biol Int 42(1):65-75 |
abstractText | Mouse urinary deoxyribonuclease I (DNase I) resembles rat and human DNase Is in terms of its proteochemical and enzymological properties. Furthermore, mouse DNase I was demonstrated to be immunologically closer to the rat than to the human enzyme. A 1176 bp full length cDNA encoding mouse DNase I was constructed from RNA obtained from the kidney and parotid glands. The amino acid sequence up to the 45th residue from the N-terminal of the mature enzyme was identical to that deduced from the cDNA sequence. This DNase I was distributed most densely in the parotid glands from the standpoint of both enzyme activity and gene transcript levels. |