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Protein Coding Gene : Kdm4d lysine (K)-specific demethylase 4D

Primary Identifier  MGI:3606484 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  244694
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin DNA binding activity; damaged DNA binding activity; and histone H3K9 demethylase activity. Acts upstream of or within DNA damage response. Located in nucleus and site of double-strand break. Part of pericentric heterochromatin. Orthologous to human KDM4D (lysine demethylase 4D).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit accumulation of histone 3 methylation in spermatids, a transient increase in testes size, wider tubules, occasional male germ cell apoptosis, and decreased body weight. However, fertility is normal. [provided by MGI curators]
  • synonyms:
  • jumonji domain containing 2D,
  • Jmjd2d,
  • Kdm4d,
  • lysine (K)-specific demethylase 4D

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Genome

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0 Canonical

0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

3 Pathways

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Expression

Gene --> Expression annotations

Phenotype

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Disease

Mouse features --> Human diseases

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