Primary Identifier | MGI:4839212 | Allele Type | Chemically induced (ENU) |
Gene | Atp4a | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | The mutation has been identified as a T to C transition at nucleotide position 863 of the transcript, in the seventh of the gene's 22 exons. It is predicted to result in replacement of serine by proline at amino acid position 282 of the encoded gastric H,K-ATPase alpha subunit. RT-PCR confirmed a 2-fold reduction in transcript expression in the stomach. |