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Allele : Atp4a<m1Btlr> ATPase, H+/K+ exchanging, gastric, alpha polypeptide; mutation 1, Bruce Beutler

Primary Identifier  MGI:4839212 Allele Type  Chemically induced (ENU)
Gene  Atp4a Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  The mutation has been identified as a T to C transition at nucleotide position 863 of the transcript, in the seventh of the gene's 22 exons. It is predicted to result in replacement of serine by proline at amino acid position 282 of the encoded gastric H,K-ATPase alpha subunit. RT-PCR confirmed a 2-fold reduction in transcript expression in the stomach.
  • mutations:
  • Single point mutation
  • synonyms:
  • sublytic,
  • sublytic
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele