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Protein Domain : Amnionless

Primary Identifier  IPR026112 Type  Family
Short Name  AMN
description  Human amnionless (AMN) is necessary for efficient absorption of vitamin B12. Defects in AMN is a cause of recessive hereditary megaloblastic anemia 1 (RH-MGA1), also known as MGA1 Norwegian type or Imerslund-Grasbeck syndrome (I-GS)[]. AMN may direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm [, ].

0 Child Features

0 Parent Features

2 Protein Domain Regions