| First Author | Anderson SA | Year | 1997 |
| Journal | Science | Volume | 278 |
| Issue | 5337 | Pages | 474-6 |
| PubMed ID | 9334308 | Mgi Jnum | J:43957 |
| Mgi Id | MGI:1099179 | Doi | 10.1126/science.278.5337.474 |
| Citation | Anderson SA, et al. (1997) Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes [see comments]. Science 278(5337):474-6 |
| abstractText | Although previous analyses indicate that neocortical neurons originate from the cortical proliferative zone, evidence suggests that a subpopulation of neocortical interneurons originates within the subcortical telencephalon. For example, gamma-aminobutyric acid (GABA)-expressing cells migrate in vitro from the subcortical telencephalon into the neocortex. The number of GABA-expressing cells in neocortical slices is reduced by separating the neocortex from the subcortical telencephalon. Finally, mice lacking the homeodomain proteins DLX-1 and DLX-2 show no detectable cell migration from the subcortical telencephalon to the neocortex and also have few GABA-expressing cells in the neocortex. |
