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Allele : Tg(Scgb1a1-rtTA)1Jaw transgene insertion 1, Jeffrey A Whitsett

Primary Identifier  MGI:2445707 Allele Type  Transgenic
Attribute String  Transactivator Gene  Tg(Scgb1a1-rtTA)1Jaw
Strain of Origin  129 and C57BL/6 Is Recombinase  false
Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Bronchopulmonary dysplasia (J:130523, J:171488).
molecularNote  The transgene is composed of 2.3 kb of rat Ugb (Scgb1a1) promoter, a reverse tetracycline responsive transactivator gene (rt-TA), and 2 kb of human growth hormone sequences, which includes introns and a polyadenylation signal. Transgene expression was confirmed by RT-PCR analysis. The rat Scgb1a1 promoter is active in respiratory epithelial cells.
  • mutations:
  • Insertion
  • synonyms:
  • CCSP-rtTA,
  • Scgb1a1-rtTA,
  • Tg(Ugb-rtTA)1Jaw,
  • CCSP<tg>,
  • CC10-rtTA,
  • CC10-rtTA,
  • Scgb1a1-rtTA,
  • CCSP-rtTA,
  • CCSP<tg>,
  • Tg(Ugb-rtTA)1Jaw
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

217 Publication categories

Trail: Allele