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Protein Domain : Prolyl 3-hydroxylase

Primary Identifier  IPR039575 Type  Family
Short Name  P3H
description  This entry represents prolyl 3-hydroxylase, including prolyl 3-hydroxylase catalyses 1-3 (P3H1-3) from humans. P3H1, also known as leprecan-1, is responsible for converting proline to 3-hydroxyproline (3Hyp) in type I collagen. P3H2 is responsible for 3-hydroxylating multiple proline sites in collagen types I, II, IV, and V []. However, P3H3 is not required for normal prolyl 3-hydroxylation on collagen chains [].

3 Child Features

0 Parent Features

7 Protein Domain Regions