| Primary Identifier | MGI:5006982 | Allele Type | Chemically induced (ENU) |
| Gene | Axin2 | Inheritance Mode | Recessive |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | ENU treatment induced a T-to-A mutation, resulting in a valine to aspartic acid substitution at amino acid 26 (p.V26D) in an invariant N-terminal sequence motif. Western blot analysis indicated protein expression was increased 1.6 and 2.2 fold in heterozygous and homozygous embryos, respectively, relative to wild-type mice. Protein half-life is increased in homozygous MEFs relative to wild-type MEFs. |
