Primary Identifier | MGI:1888999 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 57875 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables enzyme inhibitor activity. Involved in negative regulation of apoptotic process and triglyceride homeostasis. Acts upstream of or within negative regulation of endothelial cell apoptotic process. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and integumental system. Orthologous to human ANGPTL4 (angiopoietin like 4). PHENOTYPE: Mice homozygous for disruptions in this gene display decreased levels of triglycerides and cholesterol and a lower increase in body fat after exposure to gut microbiota. [provided by MGI curators] |