Primary Identifier | MGI:5911996 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lrig3 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 1 and a neomycin resistance gene cassette and a second loxP site were inserted into intron 1. Exon 1 was deleted through subsequent cre-mediated recombination. Western blots and RT-PCR confirmed the lack of expression from the knockout allele. |