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Protein Coding Gene : Tgm4 transglutaminase 4 (prostate)

Primary Identifier  MGI:3027002 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  331046
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Acts upstream of or within mating plug formation. Predicted to be located in Golgi apparatus. Predicted to be active in collagen-containing extracellular matrix. Is expressed in anterior prostate gland; prostate gland dorsolateral lobe; and ventral prostate gland. Orthologous to human TGM4 (transglutaminase 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired copulatory plug formation, reduced fertilization and few litters sired. [provided by MGI curators]
  • synonyms:
  • Tgm4,
  • RIKEN cDNA 9530008N10 gene,
  • 9530008N10Rik,
  • transglutaminase 4 (prostate),
  • Eapa1,
  • experimental autoimmune prostatitis antigen 1

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