Primary Identifier | IPR042502 | Type | Family |
Short Name | TM7SF3 |
description | TM7SF3 is a seven transmembrane orphan receptor which inhibits cytokine-induced death of pancreatic beta cells []. It also maintains protein homeostasis and promotes cell survival through attenuation of ER stress. Interestingly, p53 promotes the expression of TM7SF3 that acts to restrict p53 activity []. |