| Primary Identifier | MGI:3574351 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Adamts1 |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was deleted via cre-mediated recombination, removing the metalloproteinase domain and, if normal splicing occurred, would result in a frame shift leading to a truncated protein containing only a pre-/pro-domain only. Northern blot using a probe containing exons 4-8 indicated the absence of transcript. Immunohistochemistry further demonstrated the absence of expression in null ovaries. |
