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Protein Coding Gene : Ccna2 cyclin A2

Primary Identifier  MGI:108069 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  12428
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables protein kinase binding activity. Acts upstream of or within positive regulation of DNA-templated transcription. Located in cytoplasm; female pronucleus; and male pronucleus. Part of cyclin A2-CDK1 complex and cyclin A2-CDK2 complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human CCNA2 (cyclin A2).
PHENOTYPE: Embryos homozygous for a targeted mutation implant in the uterine wall, but fail to develop past 5.5 dpc. Notably, mutant embryos develop normally from the four-cell to the post-implantation stage in the absence of detectable maternally-derived gene products. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-1805,
  • Ccna,
  • MGI:2139562,
  • Ccn-1,
  • MGD-MRK-1807,
  • MGD-MRK-1809,
  • MGD-MRK-2264,
  • MGD-MRK-37106,
  • cyclin A2,
  • cyclin A,
  • expressed sequence AA408589,
  • CycA2,
  • Ccn1,
  • AA408589,
  • Cyca,
  • Ccna2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

57 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For