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Protein Coding Gene : Tgds TDP-glucose 4,6-dehydratase
Primary Identifier  MGI:1923605 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  76355
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable dTDP-glucose 4,6-dehydratase activity. Predicted to be involved in nucleotide-sugar metabolic process. Is expressed in several structures, including alimentary system; cranium; eye; integumental system; and telencephalon. Human ortholog(s) of this gene implicated in Catel Manzke syndrome. Orthologous to human TGDS (TDP-glucose 4,6-dehydratase).
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit micrognathia and cleft palate. [provided by MGI curators]
  • synonyms:
  • 2610017J16Rik,
  • AI648925,
  • TDP-glucose 4,6-dehydratase,
  • 2610025M23Rik,
  • MGI:2145686,
  • MGI:1917161,
  • RIKEN cDNA 2610017J16 gene,
  • Tgds,
  • RIKEN cDNA 2610025M23 gene,
  • expressed sequence AI648925
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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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