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Protein Coding Gene : Socs4 suppressor of cytokine signaling 4
Primary Identifier  MGI:1914546 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  67296
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within negative regulation of signal transduction. Predicted to be located in cytosol. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in ganglia; sensory organ; thymus primordium; and ventricular layer. Orthologous to human SOCS4 (suppressor of cytokine signaling 4).
PHENOTYPE: Homozygosity for a knockout allele leads to increased susceptibility to influenza-virus-induced morbidity and mortality. [provided by MGI curators]
  • synonyms:
  • suppressor of cytokine signaling 4,
  • expressed sequence AI427843,
  • Socs7,
  • AU015727,
  • MGI:2145722,
  • AU015859,
  • RIKEN cDNA A730004F22 gene,
  • MGI:2145724,
  • expressed sequence AU015859,
  • AI427843,
  • A730004F22Rik,
  • expressed sequence AU015727,
  • suppressor of cytokine signaling 7,
  • MGI:2145633,
  • Socs4,
  • 3110032M18Rik,
  • RIKEN cDNA 3110032M18 gene
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