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Protein Coding Gene : Gabra6 gamma-aminobutyric acid type A receptor subunit alpha 6

Primary Identifier  MGI:95618 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  14399
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and inhibitory synapse assembly. Predicted to act upstream of or within chloride transport. Is active in cerebellar Golgi cell to granule cell synapse. Is expressed in central nervous system and retina. Orthologous to human GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6).
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile with normal cerebellar cytoarchitecture and normal responses to ethanol, pentobarbital and general anesthetics. Mice homozygous for a reporter allele are behaviorally normal and lack a cochlear phenotype. [provided by MGI curators]
  • synonyms:
  • Gabra6,
  • gamma-aminobutyric acid type A receptor subunit alpha 6,
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6,
  • Gabra-6,
  • MGD-MRK-9932,
  • alpha6,
  • MGD-MRK-9926,
  • GABA-ARalpha6

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

3 Driver For