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Protein Domain : von Willebrand factor A domain-containing protein 1

Primary Identifier  IPR030758 Type  Family
Short Name  Vwa1
description  von Willebrand factor A domain-containing protein 1 (Vwa1, WARP) is expressed predominantly in chondrocytes [, ], where it interacts with collagen VI-containing microfibrils and might function as an adapter protein in the cartilage pericellular matrix []. It is also expressed in the vasculature of neural tissues, in basement membrane structures of the peripheral nervous system, and in skeletal and cardiac muscle []. Studies in mice indicate that WARP is not essential for basement membrane formation or musculoskeletal development, but it has critical roles in the structure and function of peripheral nerves [].

0 Child Features

0 Parent Features

1 Protein Domain Regions