First Author | Formstone CJ | Year | 1993 |
Journal | Genomics | Volume | 16 |
Issue | 1 | Pages | 289-91 |
PubMed ID | 8486377 | Mgi Jnum | J:4374 |
Mgi Id | MGI:52867 | Doi | 10.1006/geno.1993.1181 |
Citation | Formstone CJ, et al. (1993) The order and orientation of a cluster of metalloproteinase genes, stromelysin 2, collagenase, and stromelysin, together with D11S385, on chromosome 11q22-q23. Genomics 16(1):289-91 |
abstractText | A cluster of metalloproteinase genes, stromelysin, fibroblast collagenase, and stromelysin 2 together with the anonymous DNA marker D11S385, was mapped using pulsed-field gel electrophoresis to a 135-kb region of chromosome 11q22-q23. The physical proximity of these markers was subsequently confirmed using two YAC clones, and their relative order was established as stromelysin 2-collagenase-stromelysin-D11S385. The pattern of marker representation in a panel of radiation-reduced chromosome 11 hybrids suggests that the metalloproteinase gene/D11S385 cluster is orientated with STMY2 closest to the centromere. |