| Primary Identifier | MGI:2145118 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 217715 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ATP binding activity; GTP binding activity; and translation initiation factor activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; nervous system development; and positive regulation of axon extension. Predicted to act upstream of or within translation. Predicted to be located in axon and cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2B complex. Predicted to be active in endoplasmic reticulum; glycinergic synapse; and postsynapse. Is expressed in early conceptus; genitourinary system; spinal ganglion; and vibrissa. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter and leukoencephalopathy with vanishing white matter 2. Orthologous to human EIF2B2 (eukaryotic translation initiation factor 2B subunit beta). |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
