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Protein Coding Gene : H2-Q9 histocompatibility 2, Q region locus 9

Primary Identifier  MGI:95938 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  110558
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables peptide antigen binding activity. Acts upstream of or within several processes, including defense response to symbiont; positive regulation of T cell mediated cytotoxicity; and positive regulation of type II interferon production. Located in external side of plasma membrane. Part of MHC class Ib protein complex. Is expressed in early conceptus; inner cell mass; and spleen.
PHENOTYPE: This locus controls a lymphocyte antigen on T- and B-cells of spleen, lymph nodes and bone marrow, but not thymus. Antigen is present (a allele) in C57BL/6, C57BL/10, C57L and 129/J; other strains tested are negative (b allele). Expression level is affected by alleles carried at B2m and H2-D1 loci. [provided by MGI curators]
  • synonyms:
  • H2-Q9,
  • histocompatibility 2, Q region locus 9,
  • MGD-MRK-13728,
  • Qa9,
  • Ped,
  • MGD-MRK-13717,
  • H-2Q9,
  • Qa-9,
  • MGD-MRK-10421,
  • MGD-MRK-10534,
  • Qa lymphocyte antigen 9,
  • MGD-MRK-13710

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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