Primary Identifier | MGI:1918590 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 71340 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in maturation of SSU-rRNA and positive regulation of rRNA processing. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in cytoplasm. Predicted to be part of methyltransferase complex and preribosome, small subunit precursor. Predicted to be active in cytosol. Is expressed in embryo; extraembryonic component; oocyte; primitive endoderm; and yolk sac. Orthologous to human RIOK1 (RIO kinase 1). PHENOTYPE: Mice homozygous for a knock-out allele show normal blastocyst formation but exhibit complete embryonic lethality prior to organogenesis. [provided by MGI curators] |