Primary Identifier | IPR045831 | Type | Domain |
Short Name | LIN9_C |
description | MuvB transcriptional regulatory complex interacts with B-Myb to form the MMB complex during S-phase of the cell cycle to activate genes required for the G2 and M phases. This is a domain found at the C terminus of LIN9, one of the core members of the MuvB complex that functions as a scaffold protein and forms a subcomplex with the C terminus of LIN152. This subcomplex forms a binding interface that recruits B-Myb to the MuvB complex which is arranged as a three-stranded antiparallel coiled-coil as the core of the structure. LIN9 contributes two helices (alpha1 and alpha2) that run antiparallel and are connected through a short linker []. |