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Protein Coding Gene : Eed embryonic ectoderm development

Primary Identifier  MGI:95286 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  13626
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in facultative heterochromatin formation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of adaxial/abaxial pattern formation; and regulation of gene expression. Located in pronucleus. Part of ESC/E(Z) complex; chromatin silencing complex; and sex chromatin. Is expressed in several structures, including branchial arch; central nervous system; early embryo; embryo mesenchyme; and urinary system. Orthologous to human EED (embryonic ectoderm development).
PHENOTYPE: Homozygous mutant mice are dwarfed and their coat color is dilute. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-11693,
  • MGI:96737,
  • embryonic ectoderm development,
  • Eed,
  • MGI:3584396,
  • lethal, Chr 7, Rinchik 5,
  • MGD-MRK-9305,
  • l(7)5Rn,
  • ENSMUSG00000039373,
  • MGI:3641985,
  • l7Rn5,
  • predicted gene, ENSMUSG00000039373,
  • MGD-MRK-11725

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

13 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For