| Primary Identifier | MGI:1343142 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 11867 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable actin filament binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to be located in actin cytoskeleton; cytoplasm; and nucleus. Predicted to be part of Arp2/3 protein complex and tubulobulbar complex. Is expressed in central nervous system; early conceptus; genitourinary system; and retina. Human ortholog(s) of this gene implicated in gastritis; immunodeficiency 71; and myelodysplastic syndrome. Orthologous to human ARPC1B (actin related protein 2/3 complex subunit 1B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal skin pigmentation and dermal fibrosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
