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Protein Coding Gene : Sult1e1 sulfotransferase family 1E, member 1
Primary Identifier  MGI:98431 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  20860
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables steroid sulfotransferase activity. Involved in estrogen metabolic process. Acts upstream of or within female pregnancy. Located in cytoplasm. Is expressed in liver; nervous system; nose; and reproductive system. Human ortholog(s) of this gene implicated in breast cancer and endometrial cancer. Orthologous to human SULT1E1 (sulfotransferase family 1E member 1).
PHENOTYPE: Homozygous null mice exhibit reduced fertility. Males exhibit abnormal testis morphology with Leydig cell hypertrophy and hyperplasia and reduced caudal sperm motility. Spontaneous fetal loss caused by placental thrombosis occurs in pregnant females. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-14619,
  • sulfotransferase, estrogen preferring,
  • Sult1e1,
  • Ste,
  • EST,
  • sulfotransferase family 1E, member 1
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4 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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